Why strength matters with GLP-1

If you’re using a GLP‑1 medication or considering one, Fitness Your Way can help you stay active, maintain strength, and build habits that last beyond medication.

When exercise is combined with GLP‑1 medications, research shows:

Approximately twice the reduction in body fat % than exercise or GLP-1 alone.1

Individuals combining GLP-1 + exercise have been shown to be more likely to achieve weight loss than GLP-1 alone.2

Evidence suggests that adding exercise to a GLP-1 regimen can help preserve muscle.3

Build strength and lean into lasting results.

Weight loss medications, including GLP-1s, may support weight loss. Combining them with movement may help improve overall health and well-being.

Enhance weight loss results. Adding movement may help improve results compared to medication alone.¹

Preserve muscle and strength. Strength-focused activity may help maintain muscle during weight changes.3

Support long-term health. Regular movement supports energy, heart health, and daily function.3

Stay consistent over time. Building a routine helps you stay active during treatment and beyond.

Strength that lasts, starts here.
Lean into strength and explore these guided workouts designed to support your routine—from strength and cardio to recovery and mobility.

Stay active your way—at home, at the gym4, or wherever you are.

Find workouts that match your energy, goals, and routine.

The Fitness Your Way program is for educational and general wellness purposes only and does not diagnose or treat any medical conditions. It is not medical advice. Consult a licensed healthcare provider before starting this program. Individual results may vary.

Tivity Health does not market, prescribe, sell, or provide GLP-1 medications.

References to third-party research are provided for informational purposes and do not constitute an endorsement. Fitness Your Way and Tivity Health are not affiliated with, and do not endorse, any medication or manufacturer.

Results are based on clinical studies and may not apply to all individuals. Individual results may vary based on health factors and program adherence.

1 Marmett, B., Martins da Silva, I., Lira, F. & Dorneles, G. (2025). Anti-obesity drugs alone or combined with exercise training in the management of obesity: A systematic review with meta-analysis. Translational Exercise Biomedicine,  2(1), 51-62. The paper includes four small RCTs (n=202; two orlistat trials; two GLP‑1/GIP or GLP‑1 RA trials including liraglutide and tirzepatide) and concludes that adding structured exercise to pharmacotherapy produces additional reductions in body weight and fat mass versus pharmacotherapy alone; evidence certainty is graded low to very low for most outcomes, with heterogeneity and risk‑of‑bias concerns.

2 Lundgren, J., Janus, C., Jensen, S., Juhl, C., Olsen, L., Christensen, R., Svane, M. & Torekov, S. (2021). Healthy weight loss maintenance with exercise, liraglutide, or both combined. The New England Journal of Medicine, 384(18), 1719-1730. In adults with obesity who completed an 8‑week low‑calorie diet, one year of combined structured exercise plus liraglutide 3.0 mg produced greater weight‑loss maintenance than either alone. Adults with obesity without diabetes; 8‑week low‑calorie diet run‑in; 52‑week randomized maintenance: supervised exercise, liraglutide 3.0 mg daily, both, or placebo. Absolute treatment differences vs placebo: exercise −4.1 kg; liraglutide −6.8 kg; combination −9.5 kg; only the combination improved insulin sensitivity and cardiorespiratory fitness.

3 Neeland IJ, Linge J, Birkenfeld AL. Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies. Diabetes Obes Metab. 2024;26(Suppl. 4):16‐27. doi:10.1111/dom.15728. This review discusses evidence that exercise, including both endurance and resistance training, may help preserve lean body mass during weight loss, including during GLP-1-based therapy.

4 Fitness locations are not owned or operated by Tivity Health, Inc. or its affiliates. Fitness Your Way membership entitles members to use the fitness location facilities and amenities available to the holder of a basic membership at the fitness locations. Facilities and amenities vary by location. Inclusion of specific fitness facilities is not guaranteed and fitness facility participation may differ by membership tier. See Program Agreement for details.

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